Contract research organizations (CRO) are constantly adopting newer technologies for cost saving and delivering best therapies to patients, cloud based solutions are one of the hot cakes which have become the preferred deployment method for many clinical application in CRO industry, Amazon Web Services (AWS), Microsoft Azure and Google cloud are comprehensive, evolving cloud computing platforms which provides a mix of infrastructure as a service (IaaS), platform as a service (PaaS) and packaged software as a service (SaaS). They use data to glean important insights which can help Clinical Research organizations to improve patient care and product development. Cloud services provides global infrastructure for building and maintaining cloud-based tools that can support data-intensive workloads including predictive analytics, machine learning, and artificial intelligence process, and analyze streaming, structured, and unstructured data sets. Deploying on Cloud platforms allows CRO’s to adapt and innovate more quickly. Cloud offers ability to store and analyze petabyte-scale data sets, using only the resources they need Simplify global collaborations, Support compliance & enhance security, improve operational efficiency, AWS, Azure and Google cloud align with major regulatory and Good clinical practices (GCP). Cloud Solutions can help CRO’s to take the next step in building robust automatic processes for making data-driven decisions that improve patient care, organizational processes, and innovative product development efforts with cost effective methods and building next generation Clinical data managers by offering unmatched Data on demand solutions to data science industry.